No significant improvements were observed in TBUT (p = 0.76) or LLT (p = 0.78). Subjects using the Bruder Compress once daily had the highest rate of compliance at 90.2% (p < 0.01). No significant difference in uncomfortable wear time was found between subjects using the Bruder Compress twice daily versus once daily (p = 0.48). In the Bruder Compress groups, there was a significant reduction in the blockage of meibomian glands (p < 0.01). After treatment, subjects using a washcloth reported more uncomfortable contact lens wear time on average (mean = 5.1 ± 2.8 h) when compared with subjects who had used the Bruder Compress in Group 1 (mean = 2.8 ± 1.6 h) (p = 0.02).
Statistical tests included a generalized linear model and one-way analysis of variance (ANOVA) to investigate treatment effect on comfortable wear time.įifty-one subjects (98% female) completed the study. Clinical assessments included tear film break-up time (TBUT), lipid layer thickness (LLT), and meibomian gland evaluation. Subject diaries were monitored for compliance and collected data on daily CL comfort upon awakening and throughout the afternoon. Fifty-one CL wearers were randomized to one of three treatment groups: application of the Bruder Compress twice a day, Bruder Compress once a day, or warm washcloth used for ten minutes twice a day without reheating.
#MOIST WARM EYE COMPRESS TRIAL#
This was a 4-week, single-center, three-arm, randomized, open-label clinical trial in subjects diagnosed with CLDE using the Contact Lens Dry Eye Questionnaire.
The purpose of this study was to investigate the effect of the Bruder Moist Heat Compress on contact lens (CL) discomfort in subjects with contact lens-related dry eye (CLDE).
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